https://sites.google.com/site/ykchoicv/multispectralhttps://sites.google.com/site/drivableregion/homeDrivable region detection is challenging since various types of road, occlusion or poor illumination condition have to be considered in a outdoor environment, particularly at night. In the past decade, Many efforts have been made to solve these problems, however, most of the already existing methods are designed for visible light cameras, which are inherently inefficient under low light conditions. In this paper, we present a drivable region detection algorithm designed for thermal-infrared cameras in order to overcome the aforementioned problems. The novelty of the proposed method lies in the utilization of on-line road initialization with a highly scene-adaptive sampling mask. Furthermore, our prior road information extraction is tailored to enforce temporal consistency among a series of images. In this paper, we also propose a large number of experiments in various scenarios (on-road, off-road and cluttered road). A total of about 6000 manually annotated images are made available in our website for the research community. Using this dataset, we compared our method against multiple state-of-theart approaches including convolutional neural network (CNN) based methods to emphasize the robustness of our approach under challenging situations.